| ORIGINAL ARTICLE |
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| Year : 2023 | Volume
: 8
| Issue : 3 | Page : 280-292 |
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Pharmaceutical standardization of Amrita Bhallataka Rasayana: A compound polyherbal Ayurvedic formulation
Yagnik D Mundadiya, Swapnil Y Chaudhari, Biswa Jyoti Patgiri
Department of Rasashastra & Bhaishajya Kalpana, Institute of Teaching and Research in Ayurveda, Jamnagar, Gujarat, India
Correspondence Address:
Yagnik D Mundadiya
Department of Rasashastra & Bhaishajya Kalpana, Institute of Teaching and Research in Ayurveda, Room No. 74, ITRA Boys Hostel, Jamnagar 361008, Gujarat
India
 Source of Support: None, Conflict of Interest: None
DOI: 10.4103/jdras.jdras_109_22
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BACKGROUND: Amrita Bhallataka Rasayana (ABR) is one such Ayurvedic polyherbal compound formulation containing Bhallataka as an integral component. It is mainly indicated for rejuvenating purpose. An interesting fact in the preparation of ABR is the quantity of sugar that is to be added as per our convenience and the form of finished product (Avaleha or Ghrita). Earlier research scholars have kept this formulation as Ghrita (medicated ghee) or Avaleha (medicated semisolid preparation) dosage form as the amount of Ghrita is more in this formulation but Paka is to be done as per Avaleha dosage form. Hence, it becomes difficult to prepare and standardize such formulations. To validate the standard manufacturing process (SMP) and quality standards of Amrita Bhallataka Rasayana. METHODS: A total of three batches of ABR were prepared and subjected to organoleptic, physicochemical, high-performance thin-layer chromatography (HPTLC), and nutritional analysis to generate an analytical profile of ABR. In phytochemical qualitative analysis, the presence of saponins, flavonoids, and tannins was assessed by using appropriate qualitative testing methods. RESULTS: Using pertinent physicochemical criteria in accordance with the Ayurvedic Pharmacopeia of India, an analysis of raw and Shodhita Bhallataka was conducted. The alkaline pH value of ABR may be observed due to protein-tannins complexes between milk and oil of Bhallataka. HPTLC was done to develop a chromatographic pattern of three samples of ABR. The average water-soluble extractive of ABR was 54.14%, whereas alcohol-soluble extractive was 19.93%. CONCLUSION: The method of preparation given in the current study for ABR may be considered standard. These preliminary parameters may be helpful as standards for further studies as they are not mentioned in the Ayurvedic Pharmacopeia of India. This study may provide certain leads toward using different proportions of sugar in the preparation of ABR. |
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