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ORIGINAL ARTICLE
Year : 2022  |  Volume : 7  |  Issue : 2  |  Page : 97-104

First-order kinetic study-based comparative shelf-life assessment of Raw Vetas (Salix alba L. stem bark) and Vetas Ghana (a semisolid form of Salix alba L. stem bark aqueous extract)


1 Department of Chemistry, Central Ayurveda Research Institute, Jhansi, Uttar Pradesh, India
2 Department of Microbiology, Central Ayurveda Research Institute, Jhansi, Uttar Pradesh, India
3 Department of Ayurveda, Central Ayurveda Research Institute, Jhansi, Uttar Pradesh, India
4 Department of Chemistry, Central Council for Research in Ayurvedic Sciences, New Delhi, India
5 Department of Ayurveda, Central Council for Research in Ayurvedic Sciences, New Delhi, India

Correspondence Address:
Dr. Vijay Kumar
Department of Chemistry, Central Ayurveda Research Institute, Jhansi 284003, Uttar Pradesh
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jdras.jdras_10_22

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BACKGROUND: Shelf-life is an important aspect of raw as well as finished drugs. Recently, shelf-life parameters have been included in the Ayurvedic Pharmacopeia of India (API). The aim of this study to evaluate the comparative long-term shelf-life study of Raw Vetas (Salix alba stem bark) and Vetas Ghana (a semisolid form of Salix alba Stem bark aqueous extract). METHODS: A stability chamber with environmental conditions 30°C ± 2°C/60% RH ± 5% was used for the long-term shelf-life study of Raw Vetas and Vetas Ghana. Physicochemical parameters like loss on drying, pH, total ash, acid insoluble ash, water extractive value, and alcohol extractive value were evaluated at a regular frequency (0th, 3rd, 6th, 9th, and 12th months). RESULTS: There are significant changes that have been observed w.r.t. physicochemical parameters analysis. Physicochemical parameters revealed that the shelf-life of Raw Vetas ranged from 31 to 66 months and the shelf-life of Vetas Ghana ranged from 38 to 62 months. CONCLUSIONS: The average shelf-life of Raw Vetas and Vetas Ghana was 41.83 and 47.50 months, respectively. This study may help to understand the shelf-life of various Ayurvedic formulations consisting of Raw Vetas and Vetas Ghana.


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